Research
Discoveries about probiotics and their effects on health.
In this section, you’ll find a collection of original articles and reports that explore the properties and mechanisms of action of Bacillus subtilis DG101 through a rigorous scientific approach. Each study outlines its objectives, methodologies, and experimental results, supporting its use in areas such as microbiota modulation, immunity, metabolism, neuroprotection, and longevity. We invite you to review each report to gain a deeper understanding of how this probiotic strain plays a role in key physiological processes and lays the foundation for new therapeutic applications.
Spore-Forming Probiotics
Spore-forming probiotics, such as Bacillus subtilis DG101, remain inactive in spore form and are resistant to extreme conditions. Once they reach the intestine, they become active and support health, making them ideal for use in food products without the need for refrigeration or loss of effectiveness.
Microbiota
The microbiota is the community of microorganisms that live in the human body and perform essential functions. When balanced—known as eubiosis—it strengthens the immune system and supports overall health. When disrupted, however, it can contribute to various diseases.
Pregnancy and Breastfeeding
During pregnancy and breastfeeding, a balanced maternal microbiota strengthens the baby’s immune system and supports epigenetic development. Taking care of it from pregnancy through the first two years of life is key to preventing disease and promoting long-term health.
Bacterial Infections
Multiple studies show that Bacillus subtilis DG101 inhibits pathogenic bacteria such as Vibrio cholerae and Candida, enhances nutrient absorption, and prevents infections through competitive exclusion. It acts as a powerful probiotic with scientifically proven immune and digestive benefits.
Diabetes
Clinical research suggests that Bacillus subtilis DG101 may help improve glucose control in people with type 2 diabetes. Its effect on the gut microbiota supports insulin response, helping to naturally regulate blood sugar levels.
Celiac Disease
The gut microbiota plays a role in celiac disease, and spore-forming probiotics like Bacillus subtilis DG101 may help improve digestion and quality of life. Its resilience and ability to break down gliadin make it a promising complement to a gluten-free diet.
Psychobiotics
The gut microbiota influences mental health through its connection with the nervous system. Probiotics like Bacillus subtilis produce beneficial compounds and, according to recent studies, may protect neurons and reduce symptoms of neurodegenerative diseases such as Parkinson’s and Alzheimer’s in animal models.
Synbiotics
Synbiotics combine probiotics and prebiotics to enhance gut health. While probiotics provide beneficial bacteria, prebiotics feed them. Their combined action supports microbiota balance and is more effective than taking prebiotics alone, especially in cases of dysbiosis.
Overweight and Obesity
A clinical study showed that Bacillus subtilis DG101, combined with a healthy diet, helped reduce body weight, fat mass, and BMI in individuals with obesity. It also improved insulin and glucose levels, highlighting its potential as a supportive tool in obesity treatments.
Gut Wellness
Gut health impacts digestion, the immune system, mood, and metabolism. Maintaining a balanced microbiota through a fiber-rich diet, probiotics, proper hydration, and healthy habits is key to preventing disease and supporting overall well-being.
Fungal Infections
Fungal infections, such as candidiasis, are caused by the overgrowth of fungi naturally present in the body. Factors like antibiotic use or immunosuppression can trigger their development. Prevention involves proper hygiene, a balanced diet, and seeking medical attention if symptoms persist.
Inmunidad contra COVID-19
Un estudio internacional demostró que Bacillus subtilis DG101 actúa como adyuvante en vacunas, generando inmunidad sistémica (IgG) y mucosal (IgA). Co-administrado con la vacuna contra COVID-19, fortaleció la respuesta inmune y la memoria, clave para prevenir reinfecciones y nuevas variantes.