Certain types of bacteria and yeasts that live on our skin, in our intestines, or in mucous membranes such as the vaginal tract can increase the risk of health issues like allergies, inflammation, colitis, constipation, ulcers, SIBO, candidiasis, and more. On the other hand, other bacteria—such as Lactobacillus, Bifidobacterium, Prevotella, and Bacillus—are associated with better bodily balance (eubiosis) and greater overall well-being.
These “good” bacteria act as probiotics, helping prevent diseases caused by harmful microorganisms (pathogens).
Various studies in Argentina and around the world have shown that Bacillus subtilis, the main component of the Kyojin probiotic, has strong potential to prevent and combat infectious diseases.
A joint study by scientists from CONICET (Argentina) and CFTRI (India) showed that B. subtilis DG101 (the probiotic strain in Kyojin), when combined with another lactic acid probiotic bacterium (Leuconostoc mesenteroides), was able to inhibit the growth of Vibrio cholerae, the bacterium responsible for cholera. This combination, applied to a traditional Indian fermented food (Malted Ragi), also enhanced its nutritional value by increasing beneficial minerals like iron and zinc, as well as healthy fatty acids. Additionally, Bacillus subtilis DG101 (Kyojin) demonstrated effectiveness against intestinal, urinary, and vaginal candidiasis in a scientific study conducted in collaboration with researchers from the European Union (Metrofood-Eurecat-Barcelona).
In addition, other studies have shown that B. subtilis can prevent harmful bacteria such as Staphylococcus aureus, Listeria monocytogenes, and Enterococcus faecalis from adhering to body tissues—a key step in the onset of many infections. This mechanism, known as “competitive exclusion,” helps prevent disease at its source.
Incluso si la infección ya comenzó, B. subtilis puede ayudar a combatirla. Investigaciones del Instituto Nacional de Salud de EE. UU. y de Asia demostraron que esta bacteria produce sustancias naturales con efectos antimicrobianos que interfieren con la comunicación entre bacterias dañinas, debilitando su capacidad de causar enfermedad.
In summary, incorporating Bacillus subtilis into your daily diet—such as through the probiotic Kyojin—not only strengthens the digestive system but also actively helps protect the entire body from infections. It acts as a functional food with benefits that go beyond basic nutrition.
Related Papers:
- Mishra y col (2021). Microbial exposure during early human development primes fetal immune cells. Cell 184, 1-16. Doi: 10.1016/J.cell.2021.04.039.
- VidyaLaxme B, Rovetto A, Grau R, and Agrawal R (2014). Synergistic effects of probiotic Leuconostoc mesenteroides and Bacillus subtilis in malted ragi (Eleucine corocana) food for antagonistic activity against Vibrio cholerae and other beneficial properties. J. Food Sci. Tech. 51 (11): 3072-82. doi: 10.1007/s13197- 012-0834-5.
- Rodriguez Ayala F, Bauman C, Bartolini M, Sabal E, Salvarrey M, Strauch M, and Grau R (2017). Transcriptional regulation of adhesive properties of Bacillus subtilis to extracellular matrix proteins through the fibronectin –binding protein YloA. Mol. Microbiol. 104 (51): 804 – 821. Doi: 10.1111/mmi.13666.
- Piewngam P, Zheng Y, Nguyen T, y col (2018). Pathogen elimination by probiotic Bacillus via signalling interference. Nature doi: 10.1038/s41586-018-0616-y.